Nature's Way Selenium, Non-Yeast Source, Potent Antioxidant, 100 Capsules (Packaging May Vary)

Works good, no hangover feeling.

Selenium was named after the moon goddess, Selene, by the Swedish chemist Jons Jakob Berzelius in 1817. Dr. Klaus Schwarz established selenium as an essential nutrient for animals in 1957, but the first selenium function in humans wasn't discovered until 1973. Dr. John Rotruck and his colleagues at the University of Wisconsin demonstrated that selenium was incorporated into molecules of an enzyme called glutathione peroxidase (GPX). This vital enzyme protects red blood cells, cell membranes and sub-cellular components against undesirable reactions with soluble peroxides. We now know that several selenium-containing proteins exist, so selenium is essential in more ways than we knew in 1973.Selenium is a component of the enzyme that is needed to produce the most active thyroid hormone. Sub-optimal amounts of selenium impair thyroid hormone function and thus affects many body functions.Selenium is a component of the enzyme that is needed to produce the thyroid hormone triiodothyronine (T3). T3 is the preponderant metabolic thyroid hormone. The selenium-containing enzyme, iodothyronine deiodinase, converts the prohormone thyroxine (T4) into T3.Selenium and sulfur are chalcogens that share many chemical properties, so the strong smell or 'odor' manymention about this product is a good thing - not a bad thing. Having taken selenium for many years, usually in the less expensive selenite form that's usually combined with yeast, the benefits of selenium are so great that anything about the smell it has were put aside long ago. And after all, you're taking something that isn't all that different, chemically, from sulfur, so what should you expect?Ideally, selenium should be supplemented in the form in which it occurs naturally in foods. In studies it was found that selenomethionine was at least 75 percent bioavailable, compared to 59 percent for sodium selenite. It has been suggested that selenomethionine, which is an organic form of selenium, is easier for the human body to absorb than selenite, which is an inorganic form. It was determined in a clinical trial that selenomethionine is absorbed 19% better than selenite.Because the l-isomer of selenomethionine (Se-met) is a major natural food-form of selenium, synthetic l-Se-met or enriched food sources thereof such as selenium yeast are appropriate supplemental forms of Se for humans; for animals, dl-Se-met is acceptable.Ingested Se-met is either metabolized directly to reactive forms of selenium or stored in place of methionine in body proteins. Se-met metabolism is closely linked to protein turnover. At constant intakes in the nutritional range, tissue Se levels increase until a steady state is established, preventing the build-up to toxic levels.Methionine is an amino acid, meaning it is a building block of protein. When you consume selenomethionine supplements, your body recognizes the selenium as the amino acid methionine and immediately incorporates it in into its protein stores. In fact, taking selenomethionine supplements results in plasma selenium stores twice as high as equivalent doses of non-organic selenium supplements such as selenate, according to the Natural Medicines Comprehensive Database.Selenium supplements such as selenomethionine are considered safe and well-tolerated when consumed in doses not exceeding the tolerable upper intake — 400 micrograms daily. However, excessive amounts may cause nausea, vomiting, abdominal pain, nail changes, fatigue, irritability, alopecia and weight loss. Selenium supplements may also interact with medications such as anticoagulants, contraceptives and schizophrenia drugs.Although selenite or selenate may be used for selenoprotein biosynthesis, only Se-met is incorporated into body proteins. This allows Se to be stored in the organism and reversibly released by normal metabolic processes, thus offering an advantage over other Se compounds, along with other possible beneficial effects. Ingested Se-met is absorbed in the small intestine via the Na+-dependent neutral amino acid transport system.Any Se-met that is not immediately metabolized is incorporated into organs with high rates of proteisynthesis such as the skeletal muscles, erythrocytes, pancreas, liver, kidney, stomach and the gastrointestinal mucosa.This is a pure, no fillers really, and high quality selemium/selenomethionine product. The reviewers here thatleave bad reviews for a selemium/selenomethionine supllement like this, mostly because they believe the 'odor' of the product is bad, are for the most part clueless. Hold your nose, if you must, and swallow the capsule. You won't taste a thing.

I have used this mineral for years with breakfast and wouldn't be without it.

Seem to be very fresh. We shall see if the do the job...

This is a great purchase! I have been concerned about thyroid issues recently. I read a great deal about this product stabilizing the thyroid and immune system. It is also reportedly supposed to decrease any symptoms of inflammation related to thyroid problems. I have been taking this product for close to a week now. I have noticed a significant decrease in the inflammation in my body, specifically in the eye area. This was recommended to me from a blog that I read on the net, which focused on healing your body through supplements and food. Versus prescribed medication from your doctor. By no means am I saying that you should not be checked out by a doctor if you're concerned about any medical symptoms. But I do think it's very important for people to be well educated in their illnesses and or treatment options. I have been taking 400 mg of Selenium daily. Thus far, I have not had any side effects that I have noticed. I also have not had any allergy issues related to this supplement. I am very pleased with this supplement and definitely will continue to use it! And is definitely worth the money. Highly recommend!

Good product

Muy Buen Producto Lo recomiendo mucho comprenlo

Too soon to give stars so right now its 3. This is my 1st bottle and like other comments mine had a terrible smell. I went to natures way website and asked them directly and this was their response :"I understand that you are concerned with the smell of this product. I am happy to help in any way that I can. Our Quality Assurance department has reviewed this occurrence in the past and their results are below.Reserve bulk samples from the complaint lot as well as from other lots were inspected. All lots were found to have a similar odor with some normal variation between lots. Prior to production, the raw materials used in this lot were laboratory tested to confirm purity and potency. After production, this lot underwent additional laboratory testing before the product was made available for sale. All lab tests were within specification. An odor is normal for this product and is not an indication of an issue with the quality of the product. If the complaint bottle was exposed to high heat and humidity it could cause an increased odor compared to bottles that were not exposed to the same heat and humidity".